Search Ontology:
ChEBI
naproxcinod
- Term ID
- CHEBI:76254
- Synonyms
-
- (S)-2-(6-Methoxy-2-naphthyl)propanoic acid 4-nitrooxybutyl ester
- 4-(nitrooxy)butyl (2S)-2-(6-methoxy-2-naphthyl)propanoate
- AZD 3582
- AZD3582
- HCT 3012
- naproxcinod
- naproxcinodum
- Naproxen-N-butyl nitrate
- Nitronaproxen
- Definition
- A carboxylic ester obtained by formal condensation of the carboxy group of naproxen with the hydroxy group of 4-(nitrooxy)butanol. A cyclooxygenase-inhibiting nitric oxide donator that is metabolised to naproxen and a nitric oxide donating moiety, effective in treatment of osteoarthritis.
- References
-
- cas:163133-43-5
- drugcentral:4674
- kegg.drug:D09568
- patent:US2008269323
- patent:WO2009000723
- patent:WO2012152438
- pubmed:16784252
- pubmed:17596112
- pubmed:19392579
- pubmed:19393822
- pubmed:19411388
- pubmed:19446261
- pubmed:19557204
- pubmed:19733721
- pubmed:19798455
- pubmed:20202489
- pubmed:20677266
- pubmed:20722026
- pubmed:20828790
- pubmed:21272053
- pubmed:21275896
- pubmed:21371681
- pubmed:21439116
- pubmed:21542252
- pubmed:21545399
- pubmed:21756233
- pubmed:22425883
- pubmed:22852285
- pubmed:22870450
- pubmed:23060406
- reaxys:8432594
- wikipedia.en:Naproxcinod
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from naproxcinod
Phenotype where environments contain naproxcinod
Phenotype modified by environments containing naproxcinod
Phenotype affecting naproxcinod
Human Disease Model