nordihydroguaiaretic acid

Term ID

CHEBI:7625

Synonyms

• 1,4-bis(3,4-dihydroxyphenyl)-2,3-dimethylbutane
• 2,3-bis(3,4-dihydroxyphenylmethyl)butane
• 4,4'-(2,3-dimethyl-1,4-butanediyl)bis(pyrocatechol)
• 4,4'-(2,3-dimethylbutane-1,4-diyl)dibenzene-1,2-diol
• 4,4'-(2,3-dimethyltetramethylene)dipyrocatechol
• beta,gamma-dimethyl-alpha,delta-bis(3,4-dihydroxyphenyl)butane
• NDGA
• nordihydroguaiaretic acid
• nordihydroguaiaretic acid (unspecified)
• norhydroguaiaretic acid
• NSC 4291

Definition

A tetrol that is butane which is substituted at positions 2 and 3 by 3,4-dihydroxybenzyl groups. Masoprocol, the meso-form found in the leaves of the creosote bush (Larrea divaricata), is a potent lipoxygenase inhibitor.

References

• cas:500-38-9
• hmdb:HMDB0012270
• kegg.compound:C10719
• lincs.smallmolecule:LSM-6507
• metacyc.compound:CPD-7661
• pubmed:12375879
• pubmed:14706572
• pubmed:15389564
• pubmed:15814253
• pubmed:16061348
• pubmed:18631321
• pubmed:20848390
• pubmed:21264886
• pubmed:21858850
• pubmed:22325100
• pubmed:22432798
• pubmed:23044922
• pubmed:23053656
• pubmed:23563831
• pubmed:23603407
• pubmed:25380600
• reaxys:9803564
• wikipedia.en:Nordihydroguaiaretic_acid

Ontology

ChEBI  ( EBI )