Search Ontology:
ChEBI
(S)-ketorolac
- Term ID
- CHEBI:76228
- Synonyms
-
- (-)-ketorolac
- (1S)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
- (S)-(-)-ketorolac
- Definition
- A 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid that has S configuration. While (S)-ketorolac is a COX1 and COX2 inhibitor, both enantiomers exhibit analgesic effects. Racemic ketorolac, known simply as ketorolac, is used (mainly as the tromethamine salt) as a potent analgesic for the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis.
- References
-
- cas:66635-92-5
- pubmed:10027870
- pubmed:10223774
- pubmed:10593468
- pubmed:15584071
- pubmed:17456651
- pubmed:19281996
- pubmed:23447046
- pubmed:9549656
- reaxys:6064296
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from (S)-ketorolac
Phenotype where environments contain (S)-ketorolac
Phenotype modified by environments containing (S)-ketorolac
Phenotype affecting (S)-ketorolac
Human Disease Model