Search Ontology:
ChEBI
ibufenac
- Term ID
- CHEBI:76158
- Synonyms
-
- (4-isobutylphenyl)acetic acid
- (p-Isobutylphenyl)acetic acid
- 4-(2-Methylpropyl)benzeneacetic acid
- 4-Isobutylphenylacetic acid
- [4-(2-methylpropyl)phenyl]acetic acid
- Dytransin
- ibufenac
- ibufenaco
- ibufenacum
- Ibunac
- Definition
- A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is replaced by a 4-isobutylphenyl group. Although it was shown to be effective in treatment of rheumatoid arthritis, the clinical use of ibufenac was discontinued due to hepatotoxic side-effects.
- References
-
- cas:1553-60-2
- drugcentral:3293
- kegg.drug:D01963
- patent:US2008014272
- patent:US2011212904
- patent:US4391814
- patent:WO2010013279
- pubmed:1479559
- pubmed:16456879
- pubmed:21128314
- pubmed:2585272
- pubmed:3215965
- pubmed:5329891
- pubmed:5657238
- pubmed:5748163
- pubmed:5752436
- pubmed:5807207
- pubmed:687781
- pubmed:7587932
- pubmed:9061203
- reaxys:2046683
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from ibufenac
Phenotype where environments contain ibufenac
Phenotype modified by environments containing ibufenac
Phenotype affecting ibufenac
Human Disease Model