benoxaprofen

Term ID

CHEBI:76114

Synonyms

(+-)-benoxaprofen
(1)-2-(4-Chlorophenyl)benzoxazole-5-propionic acid
2-(4-Chlorophenyl)-alpha-methyl-5-benzoxazoleacetic acid
2-(p-chlorophenyl)-alpha-methyl-5-benzoxazoleacetic acid
2-[2-(4-chlorophenyl)-1,3-benzoxazol-5-yl]propanoic acid
benoxaprofen
benoxaprofene
benoxaprofeno
benoxaprofenum
DL-benoxaprofen
Lilly 90459

Definition

A monocarboxylic acid that is propionic acid substituted at position 2 by a 2-(4-chlorophenyl)-1,3-benzoxazol-5-yl group. It was used as a non-steroidal anti-inflammatory drug until 1982 when it was withdrawn from the market due to adverse side-effects including liver necrosis, photosensitivity, and carcinogenicity in animals.

References

cas:51234-28-7
drugbank:DB04812
drugcentral:311
kegg.drug:D03080
patent:DE2324443
patent:US3912748
patent:US4391814
patent:US6338855
patent:WO2008020270
pubmed:19439485
pubmed:19773537
pubmed:21128314
pubmed:22514582
pubmed:23250699
pubmed:2413686
pubmed:2833969
pubmed:2947294
pubmed:3981515
pubmed:6407402
pubmed:6526401
pubmed:6645654
pubmed:6813936
pubmed:6993669
pubmed:6993670
pubmed:6993671
pubmed:6993672
pubmed:7044799
pubmed:7044801
pubmed:7084283
pubmed:7084287
pubmed:7221526
reaxys:1085080
wikipedia.en:Benoxaprofen

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from benoxaprofen

Phenotype where environments contain benoxaprofen

Phenotype modified by environments containing benoxaprofen

Phenotype affecting benoxaprofen

Human Disease Model