afatinib dimaleate

Term ID

CHEBI:76003

Synonyms

(2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[(3S)-tetrahydrofuran-3-yloxy]quinazolin-6-yl}-4-(dimethylamino)but-2-enamide di[(2Z)-but-2-enedioate]
Afatinib maleate
BIBW 2992MA2
Gilotrif

Definition

A maleate salt obtained by combining afatinib with two molar equivalents of maleic acid. Used for the first-line treatment of patients with metastatic non-small cell lung cancer.

References

CAS:850140-73-7
DrugBank:DB08916
KEGG:D09733
PMID:23982599
Patent:US2005085495
Patent:WO2012121764
Patent:WO2013052157
Reaxys:14383062
Wikipedia:Afatinib

Ontology

ChEBI ( EBI )

Relationships

is a type of: maleate salt

maleate salt Show first 5 Terms
has_part: afatinib

afatinib Show first 5 Terms
has_role: antineoplastic agent tyrosine kinase inhibitor

antineoplastic agent tyrosine kinase inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from afatinib dimaleate

Phenotype where environments contain afatinib dimaleate

Phenotype modified by environments containing afatinib dimaleate

Human Disease / Model Data

Citations