nitrazepam

Term ID

CHEBI:7581

Synonyms

• 1,3-dihydro-7-nitro-5-phenyl-2H-1,4-benzodiazepin-2-one
• 2,3-dihydro-7-nitro-5-phenyl-1H-1,4-benzodiazepin-2-one
• 7-nitro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one
• 7-nitro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one
• 7-nitro-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one
• Apodorm
• Atempol
• Benzalin
• Calsmin
• Dormicum
• Eatan
• Eunoctin
• Gerson
• Hipnax
• Hipsal
• Ibrovek
• Imeson
• Imesont
• Mogadon
• N-desmethylnimetazepam
• Nelbon
• Nelmat
• Neozepam
• Neuchlonic
• Nitrados
• nitrazepam
• nitrazepamum
• Paxisyn
• Pelson
• Persopit
• Radedorm
• Relact
• Remnos
• Ro 4-5360
• Ro 5-3059
• Somitran
• Sonebon
• Sonnolin
• Surem
• Trazenin
• Unisomnia

Definition

A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one which is substituted at positions 5 and 7 by phenyl and nitro groups, respectively. It is used as a hypnotic for the short-term management of insomnia and for the treatment of epileptic spasms in infants (West's syndrome).

References

• cas:146-22-5
• drugbank:DB01595
• drugcentral:1945
• hmdb:HMDB0015534
• kegg.compound:C07487
• kegg.drug:D00531
• lincs.smallmolecule:LSM-5681
• patent:US3121076
• pubmed:10030438
• pubmed:15637997
• pubmed:18603831
• pubmed:19557123
• pubmed:23085494
• pubmed:23245766
• pubmed:331868
• pubmed:578380
• pubmed:6143468
• pubmed:6926838
• pubmed:6988458
• pubmed:7037262
• reaxys:757185
• wikipedia.en:Nitrazepam

Ontology

ChEBI  ( EBI )

Resources

CTD