ikarugamycin

Term ID

CHEBI:75276

Synonyms

• (2R,3R,3aS,5aR,5bS,7Z,14S,19E,20aS,21aR,21bR)-3-ethyl-22-hydroxy-2-methyl-2,3,3a,5a,5b,6,10,11,12,13,14,15,20a,21,21a,21b-hexadecahydro-1H-14,17-(metheno)-as-indaceno[3,2-k][1,6]diazacycloheptadecine-9,16,18(17H)-trione

Definition

A polyketide macrolactam containing a tetramic acid (pyrrolidine-2,4-dione) ring system. It is isolated from Streptomyces as an antibiotic with antiprotozoal and cytotoxic activities.

References

• cas:36531-78-9
• knapsack:C00018842
• patent:GB2120098
• pubmed:11160755
• pubmed:1572375
• pubmed:21392513
• pubmed:23584286
• pubmed:24519911
• pubmed:24706593
• pubmed:25711294
• pubmed:27392092
• pubmed:28128495
• pubmed:31944405
• pubmed:32021101
• pubmed:32052979
• pubmed:34286109
• pubmed:34681057
• pubmed:37419511
• pubmed:4625358
• reaxys:771794

Ontology

ChEBI  ( EBI )

Resources

CTD