nimustine

Term ID

CHEBI:75270

Synonyms

1-(4-Amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea
3-(4-Amino-2-methyl-5-pyrimidinyl)methyl-1-(2-chloroethyl)-1-nitrosourea
3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-1-(2-chloroethyl)-1-nitrosourea
nimustina
nimustine
nimustinum

Definition

An organochlorine compound that is urea in which the two hydrogens on one of the amino groups are replaced by nitroso and 2-chloroethyl groups and one hydrogen from the other amino group is replaced by a 4-amino-2-methylpyrimidin-5-ylmethyl] group. An antineoplastic agent especially effective against malignant brain tumors.

References

cas:42471-28-3
drugcentral:3384
kegg.drug:D08276
pubmed:21420247
pubmed:23106822
pubmed:23228988
pubmed:23578789
pubmed:23651604
pubmed:23912878
reaxys:685903
wikipedia.en:Nimustine

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

Phenotype

Phenotype resulting from nimustine

Phenotype where environments contain nimustine

Phenotype modified by environments containing nimustine

Phenotype affecting nimustine

Human Disease Model