neostigmine

Term ID

CHEBI:7514

Synonyms

• (m-Hydroxyphenyl)trimethylammonium dimethylcarbamate
• 3-[(dimethylcarbamoyl)oxy]-N,N,N-trimethylanilinium
• 3-Trimethylammoniumphenyl N,N-dimethylcarbamate
• Eustigmin
• Eustigmine
• m-Trimethylammoniumphenyldimethylcarbamate
• Prostigmine
• Vagostigmine

Definition

A quaternary ammonium ion comprising an anilinium ion core having three methyl substituents on the aniline nitrogen, and a 3-[(dimethylcarbamoyl)oxy] substituent at position 3. It is a parasympathomimetic which acts as a reversible acetylcholinesterase inhibitor.

References

• cas:59-99-4
• drugbank:DB01400
• drugcentral:1897
• hmdb:HMDB0015472
• kegg.compound:C07258
• kegg.drug:D08261
• lincs.smallmolecule:LSM-5360
• pubmed:7200780
• pubmed:8584207
• reaxys:3615946
• wikipedia.en:Neostigmine

Ontology

ChEBI  ( EBI )

Resources

CTD