Search Ontology:
ChEBI

naltrexone

Term ID
CHEBI:7465
Synonyms
  • 17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one
  • 17-(Cyclopropylmethyl)-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one
  • 3,14-dihydroxy-17-(cyclopropylmethyl)-4,5alpha-epoxymorphinan-6-one
  • N-Cyclopropylmethyl-14-hydroxydihydromorphinone
  • N-Cyclopropylmethylnoroxymorphone
  • Naltrexone
Definition
An organic heteropentacyclic compound that is naloxone substituted in which the allyl group attached to the nitrogen is replaced by a cyclopropylmethyl group. A μ-opioid receptor antagonist, it is used to treat alcohol dependence.
References
  • cas:16590-41-3
  • drugbank:DB00704
  • drugcentral:1765
  • hmdb:HMDB0014842
  • kegg.compound:C07253
  • kegg.drug:D05113
  • lincs.smallmolecule:LSM-3962
  • patent:US3332950
  • pubmed:17023477
  • pubmed:24107112
  • pubmed:24659754
  • pubmed:27690505
  • pubmed:27700187
  • pubmed:27787292
  • pubmed:27813192
  • pubmed:27875802
  • pubmed:27922226
  • pubmed:27936293
  • pubmed:27987236
  • pubmed:28011389
  • pubmed:28029718
  • pubmed:28044452
  • pubmed:28061017
  • pubmed:28068780
  • pubmed:28106937
  • pubmed:28118565
  • pubmed:28130024
  • pubmed:28144772
  • pubmed:28153651
  • pubmed:28161142
  • pubmed:28168894
  • pubmed:28184294
  • reaxys:3596648
  • wikipedia.en:Naltrexone
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
Phenotype
Phenotype resulting from naltrexone
Phenotype where environments contain naltrexone
Phenotype modified by environments containing naltrexone
Phenotype affecting naltrexone
Human Disease Model