Search Ontology:
ChEBI
acivicin
- Term ID
- CHEBI:74545
- Synonyms
-
- (2S)-amino[(5S)-3-chloro-4,5-dihydro-1,2-oxazol-5-yl]acetic acid
- (alpha-S,5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid
- (alphaS,5S)-alpha-amino-3-chloro-2-isoxazoline-5-acetic acid
- acivicin
- acivicine
- acivicino
- acivicinum
- Antibiotic AT 125
- AT 125
- AT-125
- NSC 163501
- NSC-163501
- U 42126
- U-42,126
- Definition
- An L-alpha-amino acid that is L-alanine in which the methyl group is replaced by a (5S)-3-chloro-4,5-dihydro-1,2-oxazol-5-yl group. A glutamine analogue antimetabolite, it interferes with glutamate metabolism and several glutamate-dependent synthetic enzymes. It is obtained as a fermentation product of Streptomyces sviceus bacteria.
- References
-
- CAS:42228-92-2
- KEGG:D02755
- MetaCyc:CPD0-1036
- PDBeChem:AVN
- PMID:11478776
- PMID:14586123
- PMID:2383250
- PMID:2894949
- PMID:3112985
- PMID:3165971
- PMID:3710919
- PMID:3915184
- PMID:6102405
- PMID:7026076
- PMID:7150366
- PMID:8060335
- PMID:9829740
- Reaxys:1074649
- Wikipedia:Acivicin
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
Show first 5 Terms
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Phenotype
Phenotype resulting from acivicin
Phenotype where environments contain acivicin
Phenotype modified by environments containing acivicin
Human Disease Model