Search Ontology:
ChEBI
nabumetone
- Term ID
- CHEBI:7443
- Synonyms
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- 4-(6-Methoxy-2-naphthalenyl)-2-butanone
- 4-(6-Methoxy-2-naphthyl)-2-butanone
- nabumetona
- nabumetone
- nabumetonum
- Relafen
- Definition
- A methyl ketone that is 2-butanone in which one of the methyl hydrogens at position 4 is replaced by a 6-methoxy-2-naphthyl group. A prodrug that is converted to the active metabolite, 6-methoxy-2-naphthylacetic acid, following oral administration. It is shown to have a slightly lower risk of gastrointestinal side effects than most other non-steroidal anti-inflammatory drugs.
- References
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- CAS:42924-53-8
- DrugBank:DB00461
- Drug_Central:1863
- HMDB:HMDB0014604
- KEGG:D00425
- LINCS:LSM-3453
- PDBeChem:NBO
- PMID:21532165
- PMID:21650014
- PMID:21674107
- PMID:21898684
- PMID:22028826
- PMID:22298755
- PMID:22381180
- PMID:22605805
- PMID:22977877
- PMID:23020786
- PMID:23129452
- PMID:23132511
- PMID:23225308
- PMID:23584048
- PMID:23781467
- PMID:23781476
- PMID:23806470
- PMID:24074034
- PMID:24083957
- Reaxys:2103472
- Wikipedia:Nabumetone
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
- is a type of
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- has_role
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Phenotype
Phenotype resulting from nabumetone
Phenotype where environments contain nabumetone
Phenotype modified by environments containing nabumetone
Human Disease Model