Search Ontology:
ChEBI
nabumetone
- Term ID
- CHEBI:7443
- Synonyms
-
- 4-(6-Methoxy-2-naphthalenyl)-2-butanone
- 4-(6-Methoxy-2-naphthyl)-2-butanone
- nabumetona
- nabumetone
- nabumetonum
- Relafen
- Definition
- A methyl ketone that is 2-butanone in which one of the methyl hydrogens at position 4 is replaced by a 6-methoxy-2-naphthyl group. A prodrug that is converted to the active metabolite, 6-methoxy-2-naphthylacetic acid, following oral administration. It is shown to have a slightly lower risk of gastrointestinal side effects than most other non-steroidal anti-inflammatory drugs.
- References
-
- cas:42924-53-8
- drugbank:DB00461
- drugcentral:1863
- hmdb:HMDB0014604
- kegg.drug:D00425
- lincs.smallmolecule:LSM-3453
- pdb-ccd:NBO
- pubmed:21532165
- pubmed:21650014
- pubmed:21674107
- pubmed:21898684
- pubmed:22028826
- pubmed:22298755
- pubmed:22381180
- pubmed:22605805
- pubmed:22977877
- pubmed:23020786
- pubmed:23129452
- pubmed:23132511
- pubmed:23225308
- pubmed:23584048
- pubmed:23781467
- pubmed:23781476
- pubmed:23806470
- pubmed:24074034
- pubmed:24083957
- reaxys:2103472
- wikipedia.en:Nabumetone
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
Phenotype
Phenotype resulting from nabumetone
Phenotype where environments contain nabumetone
Phenotype modified by environments containing nabumetone
Phenotype affecting nabumetone
Human Disease Model