gadoteric acid

Term ID

CHEBI:73732

Synonyms

• [2,2',2'',2'''-(1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrayl-kappa(4)N(1),N(4),N(7),N(10))tetraacetato(3-)]gadolinium
• DOTA-Gd
• gadoteric acid
• Gd-DOTA

Definition

A gadolinium coordination entity consisting of DOTA in which the four amino groups are bound to a central gadolinium atom. It is used (as its meglumine salt) in magnetic resonance imaging (MRI) in brain (intracranial), spine and associated tissues of patients ages 2 years and older, to detect and visualise areas with disruption of the blood brain barrier and/or abnormal vascularity of the central nervous system.

References

• cas:72573-82-1
• kegg.drug:D08007
• patent:WO2005070400
• pmc:PMC3106454
• pubmed:18090230
• pubmed:21555197
• pubmed:21786126
• pubmed:22760854
• reaxys:17968462
• wikipedia.en:Gadoteric_acid

Ontology

ChEBI  ( EBI )