gadoterate meglumine

Term ID

CHEBI:73727

Synonyms

• 1-deoxy-1-(methylazaniumyl)-D-glucitol [2,2',2'',2'''-(1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrayl-kappa(4)N(1),N(4),N(7),N(10))tetraacetato(4-)]gadolinate(1-)
• [2,2',2'',2'''-(1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrayl-kappa(4)N(1),N(4),N(7),N(10))tetraacetato(3-)]gadolinium--1-deoxy-1-(methylamino)-D-glucitol (1/1)
• Gadolinium-DOTA meglumine
• Gd-DOTA meglumine
• Meglumine gadopentate
• Meglumine gadoterate

Definition

An organoammonium salt obtained by reaction of gadoteric acid with one equivalent of 1-deoxy-1-(methylamino)-D-glucitol (meglumine). It is used in magnetic resonance imaging (MRI) in brain (intracranial), spine and associated tissues of patients ages 2 years and older, to detect and visualise areas with disruption of the blood brain barrier and/or abnormal vascularity of the central nervous system.

References

• cas:92943-93-6
• kegg.drug:D03355
• pubmed:20407903
• pubmed:21045181
• pubmed:21339348
• pubmed:21577130
• pubmed:21890295
• pubmed:21904991
• pubmed:22068227
• pubmed:22109336
• pubmed:22167518
• pubmed:22344402
• pubmed:22543971
• pubmed:22578838
• pubmed:22592612
• pubmed:22772150
• pubmed:23211552
• pubmed:23212275
• pubmed:23262793
• pubmed:23297321
• wikipedia.en:Gadoteric_acid

Ontology

ChEBI  ( EBI )