Search Ontology:
ChEBI
(-)-noscapine
- Term ID
- CHEBI:73237
- Synonyms
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- (-)-alpha-narcotine
- (-)-narcotine
- (3S)-6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-2-benzofuran-1(3H)-one
- alpha-Narcotine
- noscapina
- noscapine
- noscapinum
- Definition
- A benzylisoquinoline alkaloid that is 1,2,3,4-tetrahydroisoquinoline which is substituted by a 4,5-dimethoxy-3-oxo-1,3-dihydro-2-benzofuran-1-yl group at position 1, a methylenedioxy group at positions 6-7 and a methoxy group at position 8. Obtained from plants of the Papaveraceae family, it lacks significant painkilling properties and is primarily used for its antitussive (cough-suppressing) effects.
- References
-
- CAS:128-62-1
- Drug_Central:1973
- HMDB:HMDB0033439
- KEGG:C09592
- KEGG:D01036
- KNApSAcK:C00001891
- LINCS:LSM-3997
- MetaCyc:CPD-14834
- PMID:22079300
- PMID:22546556
- PMID:22653730
- PMID:22671862
- PMID:22733149
- PMID:22848370
- PMID:22935070
- PMID:23117045
- Reaxys:99933
- Wikipedia:Noscapine
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
- is a type of
- has_functional_parent
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- has_role
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Phenotype
Phenotype resulting from (-)-noscapine
Phenotype where environments contain (-)-noscapine
Phenotype modified by environments containing (-)-noscapine
Human Disease Model