papulacandin

Term ID

CHEBI:72596

Synonyms

papulacandins

Definition

Any of the carbohydrate-containing antibiotic compounds obtained from the deuteromycetous fungus Papularia sphaerosperma and generally consisting of o-orsellinic acid linked via a spirocyclic structure to a lactose moiety with two different side-chains: a shorter fatty-acid chain at the O-(6') position and a longer side-chain at the O-(3) position of the glucose moiety. Papulacandin D, the simplest member of the papulacandin family, lacks the O-(6'-acyl-beta-galactoside) at the O-(4) position of the glucose residue. The papulacandins show potent antifungal activity against Candida albicans, Geotrichum lactis, Saccharomyces cerevisiae, and Pneumocytis carinii, but are inactive against filamentous fungi, bacteria, and protazoa.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: 2-benzofurans C-glycosyl compound carbohydrate-containing antibiotic fatty acid ester spiroketal

2-benzofurans C-glycosyl compound carbohydrate-containing antibiotic fatty acid ester spiroketal Show first 5 Terms
has subtype: papulacandin A papulacandin B papulacandin C papulacandin D

papulacandin A papulacandin B papulacandin C papulacandin D Show first 5 Terms
has_functional_parent: o-orsellinic acid

o-orsellinic acid Show first 5 Terms

Phenotype

Phenotype resulting from papulacandin

Phenotype where environments contain papulacandin

Phenotype modified by environments containing papulacandin

Human Disease / Model Data

Citations