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ChEBI

papulacandin

Term ID
CHEBI:72596
Synonyms
  • papulacandins
Definition
Any of the carbohydrate-containing antibiotic compounds obtained from the deuteromycetous fungus Papularia sphaerosperma and generally consisting of o-orsellinic acid linked via a spirocyclic structure to a lactose moiety with two different side-chains: a shorter fatty-acid chain at the O-(6') position and a longer side-chain at the O-(3) position of the glucose moiety. Papulacandin D, the simplest member of the papulacandin family, lacks the O-(6'-acyl-beta-galactoside) at the O-(4) position of the glucose residue. The papulacandins show potent antifungal activity against Candida albicans, Geotrichum lactis, Saccharomyces cerevisiae, and Pneumocytis carinii, but are inactive against filamentous fungi, bacteria, and protazoa.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has subtype
has_functional_parent
Phenotype
Phenotype resulting from papulacandin
Phenotype where environments contain papulacandin
Phenotype modified by environments containing papulacandin
Human Disease Model