Search Ontology:
ChEBI
cabozantinib
- Term ID
- CHEBI:72317
- Synonyms
-
- BMS 907351
- BMS-907351
- N-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
- XL 184
- XL-184
- XL184
- Definition
- A dicarboxylic acid diamide that is N-phenyl-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide in which the hydrogen at position 4 on the phenyl ring is substituted by a (6,7-dimethoxyquinolin-4-yl)oxy group. A multi-tyrosine kinase inhibitor, used (as its malate salt) for the treatment of progressive, metastatic, medullary thyroid cancer.
- References
-
- CAS:849217-68-1
- Drug_Central:4715
- KEGG:D10062
- LINCS:LSM-1195
- PMID:20127563
- PMID:21314233
- PMID:21460789
- PMID:21606412
- PMID:21613405
- PMID:21860001
- PMID:21862995
- PMID:21926191
- PMID:22146228
- PMID:22585997
- PMID:23104465
- PMID:23169517
- PMID:23248244
- PMID:23292257
- PMID:23292795
- PMID:23319755
- PMID:23319797
- PMID:23319867
- PMID:23335077
- PMID:23337762
- PMID:23337763
- PMID:23375349
- Patent:WO2012109510
- Reaxys:18631644
- Wikipedia:Cabozantinib
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
- inverse has_part
-
Phenotype
Phenotype resulting from cabozantinib
Phenotype where environments contain cabozantinib
Phenotype modified by environments containing cabozantinib
Human Disease Model