Search Ontology:
ChEBI
cabozantinib
- Term ID
- CHEBI:72317
- Synonyms
-
- BMS 907351
- BMS-907351
- N-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
- XL 184
- XL-184
- XL184
- Definition
- A dicarboxylic acid diamide that is N-phenyl-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide in which the hydrogen at position 4 on the phenyl ring is substituted by a (6,7-dimethoxyquinolin-4-yl)oxy group. A multi-tyrosine kinase inhibitor, used (as its malate salt) for the treatment of progressive, metastatic, medullary thyroid cancer.
- References
-
- cas:849217-68-1
- drugcentral:4715
- kegg.drug:D10062
- lincs.smallmolecule:LSM-1195
- patent:WO2012109510
- pubmed:20127563
- pubmed:21314233
- pubmed:21460789
- pubmed:21606412
- pubmed:21613405
- pubmed:21860001
- pubmed:21862995
- pubmed:21926191
- pubmed:22146228
- pubmed:22585997
- pubmed:23104465
- pubmed:23169517
- pubmed:23248244
- pubmed:23292257
- pubmed:23292795
- pubmed:23319755
- pubmed:23319797
- pubmed:23319867
- pubmed:23335077
- pubmed:23337762
- pubmed:23337763
- pubmed:23375349
- reaxys:18631644
- wikipedia.en:Cabozantinib
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from cabozantinib
Phenotype where environments contain cabozantinib
Phenotype modified by environments containing cabozantinib
Phenotype affecting cabozantinib
Human Disease Model