cabozantinib

Term ID

CHEBI:72317

Synonyms

BMS 907351
BMS-907351
N-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
XL 184
XL-184
XL184

(all 6)

Definition

A dicarboxylic acid diamide that is N-phenyl-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide in which the hydrogen at position 4 on the phenyl ring is substituted by a (6,7-dimethoxyquinolin-4-yl)oxy group. A multi-tyrosine kinase inhibitor, used (as its malate salt) for the treatment of progressive, metastatic, medullary thyroid cancer.

References

(all 29)

Ontology

ChEBI ( EBI )

Relationships

is a type of: aromatic ether dicarboxylic acid diamide organofluorine compound quinolines

aromatic ether dicarboxylic acid diamide organofluorine compound quinolines Show first 5 Terms
has_role: antineoplastic agent tyrosine kinase inhibitor

antineoplastic agent tyrosine kinase inhibitor Show first 5 Terms
inverse has_part: cabozantinib malate

cabozantinib malate Show first 5 Terms

Phenotype

Phenotype resulting from cabozantinib

Phenotype where environments contain cabozantinib

Phenotype modified by environments containing cabozantinib

Phenotype affecting cabozantinib

Human Disease Model