pasireotide

Term ID

CHEBI:72312

Synonyms

cyclo((4R)-4-(2-aminoethylcarbamoyloxy)-L-prolyl-L-phenylglycyl-D-tryptophyl-L-lysyl-4-O-benzyl-L-tyrosyl-L- phenylalanyl-)
cyclo[(2S)-2-phenylglycyl-D-tryptophyl-L-lysyl-O-benzyl-L-tyrosyl-L-phenylalanyl-(4R)-4-{[(2-aminoethyl)carbamoyl]oxy}-L-prolyl]
pasireotida
pasireotide
pasireotidum
SOM 230
SOM-230
SOM230

(all 8)

Definition

A six-membered homodetic cyclic peptide composed from L-phenylglycyl, D-tryptophyl, L-lysyl, O-benzyl-L-tyrosyl, L-phenylalanyl and modified L-hydroxyproline residues joined in sequence. A somatostatin analogue with pharmacologic properties mimicking those of the natural hormone somatostatin; used (as its diaspartate salt) for treatment of Cushing's disease.

References

(all 28)

Ontology

ChEBI ( EBI )

Relationships

is a type of: homodetic cyclic peptide peptide hormone

homodetic cyclic peptide peptide hormone Show first 5 Terms
has_role: antineoplastic agent

antineoplastic agent Show first 5 Terms
inverse is_conjugate_acid_of: pasireotide(2+)

pasireotide(2+) Show first 5 Terms
is_conjugate_base_of: pasireotide(2+)

pasireotide(2+) Show first 5 Terms

Phenotype

Phenotype resulting from pasireotide

Phenotype where environments contain pasireotide

Phenotype modified by environments containing pasireotide

Phenotype affecting pasireotide

Human Disease Model