Search Ontology:
ChEBI
lomitapide
- Term ID
- CHEBI:72297
- Synonyms
-
- AEGR 733
- AEGR 773
- AEGR-773
- AEGR733
- AEGR773
- BMS 201038
- BMS201038
- Lojuxta
- lomitapida
- lomitapide
- lomitapidum
- N-(2,2,2-trifluoroethyl)-9-{4-[4-({[4'-(trifluoromethyl)biphenyl-2-yl]carbonyl}amino)piperidin-1-yl]butyl}-9H-fluorene-9-carboxamide
- Definition
- A member of the class of benzamides obtained by formal condensation of the carboxy group of 4'-(trifluoromethyl)biphenyl-2-carboxylic acid with the primary amino group of 9-[4-(4-aminopiperidin-1-yl)butyl]-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamide. Used (as its mesylate salt) as a complement to a low-fat diet and other lipid-lowering treatments in patients with homozygous familial hypercholesterolemia.
- References
-
- cas:182431-12-5
- drugbank:DB08827
- drugcentral:4721
- kegg.drug:D09637
- patent:US2003162788
- patent:US2008161279
- patent:US2010273829
- patent:US2011288064
- patent:US2011288110
- patent:US2012035204
- patent:US2012071458
- pubmed:17215532
- pubmed:20127562
- pubmed:21846156
- pubmed:22963620
- pubmed:23122767
- pubmed:23122768
- pubmed:23147576
- pubmed:24366202
- pubmed:25257075
- pubmed:25702706
- pubmed:26120010
- pubmed:26686567
- pubmed:27055957
- pubmed:27232459
- pubmed:27785928
- pubmed:28154305
- pubmed:28239069
- pubmed:28255870
- pubmed:28432645
- pubmed:28598687
- pubmed:28716835
- reaxys:13754976
- wikipedia.en:Lomitapide
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from lomitapide
Phenotype where environments contain lomitapide
Phenotype modified by environments containing lomitapide
Phenotype affecting lomitapide
Human Disease Model