Search Ontology:
ChEBI

retaspimycin

Term ID
CHEBI:71975
Synonyms
  • (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-(allylamino)-13,20,22-trihydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3-oxo-2-azabicyclo[16.3.1]docosa-1(22),4,6,10,18,20-hexaen-9-yl carbamate
  • retaspimycin
Definition
An ansamycin that is tanespimycin in which the benzoquinone moiety has been reduced to the corresponding hydroquinone. A semi-synthetic analogue of geldanamycin, it is used (generally as the hydrochloride salt) in cancer treatment.
References
  • CAS:857402-23-4
  • KEGG:D09375
  • Patent:US2006205705
  • Patent:US2008255080
  • Patent:WO2005063714
  • Patent:WO2005095347
  • Patent:WO2007002093
  • Patent:WO2010135426
  • Reaxys:11329862
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_functional_parent
has_role
inverse is_conjugate_acid_of
is_conjugate_base_of
Phenotype
Phenotype resulting from retaspimycin
Phenotype where environments contain retaspimycin
Phenotype modified by environments containing retaspimycin
Human Disease Model