BGT226 free base

Term ID

CHEBI:71967

Synonyms

8-(6-methoxypyridin-3-yl)-3-methyl-1-[4-(piperazin-1-yl)-3-(trifluoromethyl)phenyl]-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one

Definition

An imidazoquinoline that is 3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]quinoline substituted at position 1 by a 3-trifluoromethyl-4-(piperazin-1-yl)phenyl group and at position 8 by a 6-methoxypyridin-3-yl group. A dual PI3K/mTOR inhibitor.

References

LINCS:LSM-6710
Patent:WO2006122806
Reaxys:12748765

Ontology

ChEBI ( EBI )

Relationships

is a type of: aromatic ether imidazoquinoline N-arylpiperazine organofluorine compound pyridines

aromatic ether imidazoquinoline N-arylpiperazine organofluorine compound pyridines Show first 5 Terms
has_role: antineoplastic agent EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor mTOR inhibitor

antineoplastic agent EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor mTOR inhibitor Show first 5 Terms
inverse is_conjugate_acid_of: BGT226(1+)

BGT226(1+) Show first 5 Terms
is_conjugate_base_of: BGT226(1+)

BGT226(1+) Show first 5 Terms

Phenotype

Phenotype resulting from BGT226 free base

Phenotype where environments contain BGT226 free base

Phenotype modified by environments containing BGT226 free base

Phenotype affecting BGT226 free base

Human Disease Model