Search Ontology:
ChEBI

retaspimycin hydrochloride

Term ID
CHEBI:71956
Synonyms
  • (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-(allylamino)-13,20,22-trihydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3-oxo-2-azabicyclo[16.3.1]docosa-1(22),4,6,10,18,20-hexaen-9-yl carbamate hydrochloride
  • 17-Allylamino-17-demethoxygeldanamycin hydroquinone hydrochloride
  • IPI 504
  • IPI-504
  • retaspimycin monohydrochloride
Definition
A hydrochloride that is the monohydrochloride salt of retaspimycin. A semi-synthetic water-soluble analogue of geldanamycin used in cancer treatment.
References
  • cas:857402-63-2
  • kegg.drug:D09376
  • patent:US2008255080
  • patent:WO2005063714
  • patent:WO2010135426
  • pubmed:17090671
  • pubmed:17395781
  • pubmed:17624530
  • pubmed:18644253
  • pubmed:18794084
  • pubmed:18852131
  • pubmed:19036086
  • pubmed:19642950
  • pubmed:19671750
  • pubmed:19860734
  • pubmed:19952119
  • pubmed:20191425
  • pubmed:20383346
  • pubmed:20940188
  • pubmed:20940293
  • pubmed:21106982
  • pubmed:21258415
  • pubmed:21383049
  • pubmed:21762967
  • pubmed:21825009
  • pubmed:21851215
  • pubmed:21907929
  • pubmed:22246317
  • pubmed:22652777
  • pubmed:23199899
  • reaxys:11329862
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from retaspimycin hydrochloride
Phenotype where environments contain retaspimycin hydrochloride
Phenotype modified by environments containing retaspimycin hydrochloride
Phenotype affecting retaspimycin hydrochloride
Human Disease Model