nisin

Term ID

CHEBI:71629

Synonyms

• E234
• EINECS 215-807-5
• N-{[(1S,4S,7S,8S,11R,14S,17R,20S)-7-{[N(2)-({(3R,9S,12S,15S,21S,22S)-21-[(N(2)-{[(6R,9S,10S,15aS)-10-({[(3R,6S,12S,15S)-12-[(2S)-butan-2-yl]-6-isobutyl-15-{[(2Z)-2-(L-isoleucylamino)but-2-enoyl]amino}-9-methylene-5,8,11,14-tetraoxo-1-thia-4,7,10,13-tetraa
• NSC 112903
• NSC-112903

Definition

A type-A lantibiotic containing 34 amino acid residues (including lanthionine (Lan), methyllanthionine (MeLan), didehydroalanine (Dha) and didehydroaminobutyric acid (Dhb)) and five thioether bridges. It is obtained by fermentation of the bacterium Lactococcus lactis and shows particular activity against Clostridium botulinum. It is used in the production of various processed foods to suppress Gram-positive spoilage and pathogenic bacteria and so extend shelf life.

References

• CAS:1414-45-5
• PMID:16247668
• PMID:21294231
• PMID:22265294
• PMID:22691226
• PMID:22850391
• Patent:US2935503
• Reaxys:8188142
• Wikipedia:Nisin

Ontology

ChEBI  ( EBI )

Resources

CTD