Search Ontology:
ChEBI

saxagliptin

Term ID
CHEBI:71272
Synonyms
  • (1S,3S,5S)-2-((2S)-Amino(3-hydroxytricyclo(3.3.1.13,7)dec-1-yl)acetyl)-2-azabicyclo(3.1.0)hexane-3-carbonitrile
  • (1S,3S,5S)-2-[(2S)-2-amino-2-(3-hydroxyadamantan-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile
  • BMS 477118
  • BMS-477118
  • saxagliptin
Definition
A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2S)-amino(3-hydroxyadamantan-1-yl)acetic acid with the amino group of (1S,3S,5S)-2-azabicyclo[3.1.0]hexane-3-carbonitrile. Used in its monohydrate form for the treatment of Type II diabetes.
References
  • cas:361442-04-8
  • drugbank:DB06335
  • drugcentral:4114
  • hmdb:HMDB0015634
  • kegg.drug:D08996
  • patent:US2005222242
  • patent:US2007172525
  • patent:WO2007078726
  • patent:WO2009022009
  • patent:WO2011125011
  • pubmed:22001114
  • pubmed:22066527
  • pubmed:22081481
  • pubmed:22098472
  • pubmed:22132773
  • pubmed:22149373
  • pubmed:22192246
  • pubmed:22221000
  • pubmed:22232748
  • pubmed:22248301
  • pubmed:22292415
  • pubmed:22313154
  • pubmed:22313172
  • pubmed:22334441
  • pubmed:22349123
  • pubmed:22475049
  • pubmed:22496391
  • pubmed:22564773
  • pubmed:22668067
  • pubmed:22776778
  • pubmed:22823746
  • pubmed:22828124
  • pubmed:22932707
  • pubmed:22943617
  • pubmed:23137182
  • reaxys:10201614
  • wikipedia.en:Saxagliptin
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from saxagliptin
Phenotype where environments contain saxagliptin
Phenotype modified by environments containing saxagliptin
Phenotype affecting saxagliptin
Human Disease Model