asenapine

Term ID

CHEBI:71253

Synonyms

(+-)-asenapine
(3aRS,12bRS)-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrole
asenapina
asenapine
asenapinum
rac-(3aR,12bR)-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrole
trans-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz(2,3:6,7)oxepino(4,5-c)pyrrole

Definition

A racemate consisting of equal amounts of (R,R)- and (S,S)-asenapine. Used as its maleate salt for the acute treatment of schizophrenia and acute treatment of manic or mixed episodes associated with bipolar I disorder with or without psychotic features.

References

cas:65576-45-6
patent:US2005119248
patent:US2006084692
patent:US2006229352
patent:WO2012038975
patent:WO2012040845
patent:WO2012123325
pubmed:21474903
pubmed:21557265
pubmed:21628604
pubmed:21755540
pubmed:21875607
pubmed:22156709
pubmed:22182459
pubmed:22198448
pubmed:22198451
pubmed:22332980
pubmed:22344545
pubmed:22362425
pubmed:22454251
pubmed:22494521
pubmed:22700206
pubmed:22726414
pubmed:22745558
pubmed:22849428
pubmed:22868059
pubmed:22877962
pubmed:22896826
pubmed:22900950
pubmed:22936407
pubmed:23095277
pubmed:23121334
reaxys:3654823
wikipedia.en:Asenapine

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from asenapine

Phenotype where environments contain asenapine

Phenotype modified by environments containing asenapine

Phenotype affecting asenapine

Human Disease Model