pralatrexate

Term ID

CHEBI:71223

Synonyms

(2S)-2-((4-((1RS)-1-((2,4-Diaminopteridin-6-yl)methyl)but-3-ynyl)benzoyl)amino)pentanedioic acid
(2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl}amino)pentanedioic acid
10-Propargyl-10-deazaaminopterin
Folotyn
HSDB 7786
N-(4-(1-((2,4-Diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-L-glutamic acid
N-{4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl}-L-glutamic acid
pralatrexate
pralatrexato
pralatrexatum

(all 10)

Definition

A pteridine that is the N-4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl derivative of L-glutamic acid. Used for treatment of Peripheral T-Cell Lymphoma, an aggressive form of non-Hodgkins lymphoma.

References

(all 35)

Ontology

ChEBI ( EBI )

Relationships

is a type of: N-acyl-L-glutamic acid pteridines terminal acetylenic compound

N-acyl-L-glutamic acid pteridines terminal acetylenic compound Show first 5 Terms
has_role: antimetabolite antineoplastic agent EC 1.5.1.3 (dihydrofolate reductase) inhibitor

antimetabolite antineoplastic agent EC 1.5.1.3 (dihydrofolate reductase) inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from pralatrexate

Phenotype where environments contain pralatrexate

Phenotype modified by environments containing pralatrexate

Phenotype affecting pralatrexate

Human Disease Model