tofacitinib

Term ID

CHEBI:71200

Synonyms

3-{(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}-3-oxopropanenitrile
CP 690550
CP-690550
Tasocitinib
tofacitinib
tofacitinibum

(all 6)

Definition

A pyrrolopyrimidine that is pyrrolo[2,3-d]pyrimidine substituted at position 4 by an N-methyl,N-(1-cyanoacetyl-4-methylpiperidin-3-yl)amino moiety. Used as its citrate salt to treat moderately to severely active rheumatoid arthritis.

References

(all 36)

Ontology

ChEBI ( EBI )

Relationships

is a type of: N-acylpiperidine nitrile pyrrolopyrimidine tertiary amino compound

N-acylpiperidine nitrile pyrrolopyrimidine tertiary amino compound Show first 5 Terms
has_role: antirheumatic drug EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor

antirheumatic drug EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor Show first 5 Terms
inverse has_part: tofacitinib citrate

tofacitinib citrate Show first 5 Terms

Phenotype

Phenotype resulting from tofacitinib

Phenotype where environments contain tofacitinib

Phenotype modified by environments containing tofacitinib

Phenotype affecting tofacitinib

Human Disease Model