liraglutide

Term ID

CHEBI:71193

Synonyms

liraglutida
liraglutide
liraglutidum
N2()-(L-histidyl-L-alanyl-L-alpha-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-alpha-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl)-N(6)-(N-hexadecanoyl-L-gamma-glutamyl)-L-lysyl
NN 2211
NN-2211
NN2211
Victoza

Definition

A lipopeptide that is an analogue of human GLP-1 in which the lysine residue at position 27 is replaced by arginine and a hexadecanoyl group attached to the remaining lysine via a glutamic acid spacer. Used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

References

cas:204656-20-2
drugbank:DB06655
drugcentral:4164
kegg.drug:D06404
patent:US2006160736
patent:WO2008011518
pubmed:21964769
pubmed:22038829
pubmed:22051096
pubmed:22245694
pubmed:22338093
pubmed:22382611
pubmed:22405264
pubmed:22443187
pubmed:22446097
pubmed:22536087
pubmed:22569791
pubmed:22587909
pubmed:22592020
pubmed:22727533
pubmed:22846777
pubmed:22851600
pubmed:22862847
pubmed:22927782
pubmed:22938097
pubmed:22958381
pubmed:22973968
pubmed:22985213
pubmed:23068961
pubmed:23082308
pubmed:23149376
reaxys:10331362
wikipedia.en:Liraglutide

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from liraglutide

Phenotype where environments contain liraglutide

Phenotype modified by environments containing liraglutide

Phenotype affecting liraglutide

Human Disease Model