carglumic acid

Term ID

CHEBI:71028

Synonyms

• (2S)-2-(carbamoylamino)pentanedioic acid
• acide carglumique
• acido carglumico
• acidum carglumicum
• Carbaglu
• Carbamino-L-glutamic acid
• Carbamylglutamic acid
• carglumic acid
• L-N-Carbamoylglutamic acid
• N-carbamoyl-L-glutamic acid
• Ureidoglutaric acid

Definition

A urea that is the N-carbamoyl derivative of L-glutamic acid. An orphan drug used to treat a deficiency in the enzyme N-acetylglutamate synthase, which leads to acute hyperammonaemia.

References

• cas:1188-38-1
• drugbank:DB06775
• drugcentral:3068
• hmdb:HMDB0015673
• kegg.compound:C05829
• kegg.drug:D07130
• metacyc.compound:N-CARBAMYL-L-GLUTAMATE
• pubmed:15055204
• pubmed:17421020
• pubmed:18234091
• pubmed:18516804
• pubmed:18604903
• pubmed:20410539
• pubmed:21207059
• pubmed:21225012
• pubmed:21403788
• pubmed:21941437
• pubmed:22858088
• reaxys:1727929
• wikipedia.en:Carglumic_acid

Ontology

ChEBI  ( EBI )

Resources

CTD