capsazepine

Term ID

CHEBI:70773

Synonyms

• 2-[2-(4-chlorophenyl)ethylamino-thiocarbonyl]-7,8-dihydroxy-2,3,4,5-tetrahydro-1H-2-benzazepine
• capsazepin
• N-(2-[4-chlorophenyl]ethyl)-1,3,4,5-tetrahydro-7,8-dihydroxy-2H-2-benzazepine-2-carbothioamide
• N-[2-(4-chlorophenyl)ethyl]-1,3,4,5-tetrahydro-7,8-dihydroxy-2H-2-benzazepine-2-carbothioamide
• N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-1,3,4,5-tetrahydro-2H-2-benzazepine-2-carbothioamide
• ST50826300

Definition

A benzazepine that is 2,3,4,5-tetrahydro-1H-2-benzazepine which is substituted by hydroxy groups at positions 7 and 8 and on the nitrogen atom by a 2-(p-chlorophenyl)ethylaminothiocarbonyl group. A synthetic analogue of capsaicin, it was the first reported capsaicin receptor antagonist.

References

• cas:138977-28-3
• lincs.smallmolecule:LSM-2983
• pubmed:1422598
• pubmed:14757700
• pubmed:15032662
• pubmed:18230728
• pubmed:20719804
• pubmed:22922338
• pubmed:8027976
• pubmed:9126180
• pubmed:9197280
• pubmed:9257928
• reaxys:7047754
• wikipedia.en:Capsazepine

Ontology

ChEBI  ( EBI )