Search Ontology:
ChEBI

dabigatran

Term ID
CHEBI:70752
Synonyms
  • dabigatran
Definition
An aromatic amide obtained by formal condensation of the carboxy group of 2-{[(4-carbamimidoylphenyl)amino]methyl}-1-methyl-1H-benzimidazole-5-carboxylic acid with the secondary amoino group of N-pyridin-2-yl-β-alanine. The active metabolite of the prodrug dabigatran etexilate, it acts as an anticoagulant which is used for the prevention of stroke and systemic embolism.
References
  • cas:211914-51-1
  • kegg.drug:D09707
  • patent:US2006222640
  • patent:US2008015176
  • patent:US6087380
  • patent:WO2004014894
  • patent:WO2006004575
  • patent:WO2006103206
  • patent:WO2008009638
  • patent:WO2008009639
  • pubmed:21956605
  • pubmed:22215856
  • pubmed:22227958
  • pubmed:22314599
  • pubmed:22378612
  • pubmed:22411291
  • pubmed:22413715
  • pubmed:22431533
  • pubmed:22458575
  • pubmed:22494098
  • pubmed:22595629
  • pubmed:22612026
  • pubmed:22645678
  • pubmed:22700854
  • pubmed:22722043
  • pubmed:22740145
  • pubmed:22786838
  • pubmed:22834159
  • pubmed:22854367
  • pubmed:23020832
  • pubmed:23476049
  • reaxys:9168207
  • wikipedia.en:Dabigatran
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from dabigatran
Phenotype where environments contain dabigatran
Phenotype modified by environments containing dabigatran
Phenotype affecting dabigatran
Human Disease Model