licarbazepine

Term ID

CHEBI:701

Synonyms

• 10,11-Dihydro-10-hydroxycarbamazepine
• 10-hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide
• 10-Hydroxycarbamazepine
• 10-Hydroxycarbazepine
• GP 47779
• licarbazepine

Definition

A dibenzoazepine that is 5H-dibenzo[b,f]azepine, reduced across the C-10,11 positions and carrying a carbamoyl substituent at the azepine nitrogen and a hydroxy function at C-10. A voltage-gated sodium channel blocker with anticonvulsant and mood-stabilizing effects, it is related to oxcarbazepine and is an active metabolite of oxcarbazepine.

References

• cas:29331-92-8
• kegg.compound:C07493
• pubmed:22322005
• pubmed:23507454
• pubmed:24123382
• pubmed:24981999
• pubmed:25261836
• pubmed:25489632
• reaxys:1540211
• wikipedia.en:Licarbazepine

Ontology

ChEBI  ( EBI )