Search Ontology:
ChEBI
latrunculin A
- Term ID
- CHEBI:69136
- Synonyms
-
- (+)-latrunculin A
- (4R)-4-[(1R,4Z,8E,10Z,12S,15R,17R)-17-hydroxy-5,12-dimethyl-3-oxo-2,16-dioxabicyclo[13.3.1]nonadeca-4,8,10-trien-17-yl]-1,3-thiazolidin-2-one
- LAT-A
- LatA
- LATRUNCULIN A
- NSC 613011
- Definition
- A bicyclic macrolide natural product consisting of a 16-membered bicyclic lactone attached to the rare 2-thiazolidinone moiety. It is obtained from the Red Sea sponge Latrunculia magnifica and from the Fiji Islands sponge Cacospongia mycofijiensis. Latrunculin A inhibits actin polymerisation, microfilament organsation and microfilament-mediated processes.
- References
-
- cas:76343-93-6
- pdb-ccd:LAR
- pubmed:10859320
- pubmed:12087066
- pubmed:17897856
- pubmed:19528469
- pubmed:20677927
- pubmed:22492972
- pubmed:22498812
- pubmed:3200109
- pubmed:3556584
- pubmed:9250716
- reaxys:4239363
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
Phenotype
Phenotype resulting from latrunculin A
Phenotype where environments contain latrunculin A
Phenotype modified by environments containing latrunculin A
Phenotype affecting latrunculin A
Human Disease Model