preaustinoid A1

Term ID

CHEBI:69026

Synonyms

methyl (5aS,7aS,8R,10S,12R,13aS,13bS)-10-hydroxy-5,5,7a,10,12,13b-hexamethyl-14-methylidene-3,9,11-trioxotetradecahydro-8,12-methanocycloocta[3,4]benzo[1,2-c]oxepine-8(5H)-carboxylate
preaustinoid A1

Definition

A meroterpenoid found in Penicillium rubrum and Penicillium species. It has been found to exhibit inhibitory activity against the production of interleukin 1-β from induced inflammasomes.

References

pdb-ccd:8SX
pubmed:14577628
pubmed:19678538
pubmed:21916432
pubmed:26396816
pubmed:29317628
reaxys:21969350

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from preaustinoid A1

Phenotype where environments contain preaustinoid A1

Phenotype modified by environments containing preaustinoid A1

Phenotype affecting preaustinoid A1

Human Disease Model