methylphenidate

Term ID

CHEBI:6887

Synonyms

• Daytrana
• dl-threo-methylphenidate
• methyl rac-threo-alpha-phenyl-alpha-2-piperidinylacetate
• methyl rac-threo-phenidylacetate
• methylphenidan
• methylphenidate
• methylphenidatum
• metilfenidato
• rac-methyl (2R)-phenyl[(2R)-piperidin-2-yl]acetate
• rac-threo-alpha-phenyl-2-piperidineacetic acid methyl ester
• rac-threo-methyl alpha-phenyl-alpha-(2-piperidyl)acetate
• threo-(+-)-methylphenidate

Definition

A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.

References

• cas:113-45-1
• cas:20748-11-2
• drugbank:DB00422
• hmdb:HMDB0014566
• kegg.compound:C07196
• kegg.drug:D04999
• patent:US2507631
• patent:US2957880
• pubmed:10786896
• pubmed:11160455
• pubmed:11862378
• pubmed:16953648
• pubmed:17201613
• pubmed:18670250
• pubmed:18978488
• pubmed:22098932
• pubmed:23104969
• pubmed:23813595
• pubmed:23975034
• pubmed:25433180
• pubmed:25449360
• pubmed:25553710
• reaxys:200061
• wikipedia.en:Methylphenidate

Ontology

ChEBI  ( EBI )

Resources

CTD