gabapentin enacarbil

Term ID

CHEBI:68840

Synonyms

gabapentin enacarbil
gabapentina enacarbilo
gabapentine enacarbil
gabapentinum enacarbilum
Horizant
XP 13512
XP-13512
XP13512
{1-[({[1-(isobutyryloxy)ethoxy]carbonyl}amino)methyl]cyclohexyl}acetic acid

Definition

A carbamate ester that is the N-[1-(isobutyryloxy)ethoxy]carbonyl derivative of [1-(aminomethyl)cyclohexyl]acetic acid. The prodrug for gabapentin, used for treatment of neuropathic pain and restless legs syndrome.

References

cas:478296-72-9
drugcentral:4177
patent:US2006229361
patent:US2007049626
patent:WO2005037784
patent:WO2005066122
patent:WO2006050514
patent:WO2008073257
patent:WO2010063002
pubmed:20200691
pubmed:20511481
pubmed:20573085
pubmed:20629607
pubmed:21179617
pubmed:21242741
pubmed:21255527
pubmed:21476956
pubmed:21527006
pubmed:21611981
pubmed:21627766
pubmed:21677899
pubmed:21897349
pubmed:22036917
pubmed:22077768
pubmed:22206794
pubmed:22298601
pubmed:22325733
pubmed:22422817
pubmed:22570552
pubmed:22664749
pubmed:22849331
pubmed:22851801
pubmed:22878573
pubmed:22937989
reaxys:10188772
wikipedia.en:Gabapentin_enacarbil

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from gabapentin enacarbil

Phenotype where environments contain gabapentin enacarbil

Phenotype modified by environments containing gabapentin enacarbil

Phenotype affecting gabapentin enacarbil

Human Disease Model