sch 210971

Term ID

CHEBI:68748

Synonyms

rel-(2S)-3-{(2R,4Z)-4-[{(1S,2R,4aS,6R,8S,8aR)-2-[(2E)-but-2-en-2-yl]-6,8-dimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl}(hydroxy)methylene]-3,5-dioxopyrrolidin-2-yl}-2-hydroxy-2-methylpropanoic acid

Definition

A member of the class of pyrrolidin-2-ones isolated from the fungal fermentation broth of Chaetomium globosum and shown to exhibit inhibitory activity against chemokine receptor CCR-5.

References

Chemspider:28283529
PMID:16872138
PMID:23519550
PMID:25885659
PMID:26360642
Reaxys:18561653

Ontology

ChEBI ( EBI )

Relationships

is a type of: carbobicyclic compound enol monocarboxylic acid octahydronaphthalenes pyrrolidin-2-ones

carbobicyclic compound enol monocarboxylic acid octahydronaphthalenes pyrrolidin-2-ones Show first 5 Terms
has_role: antifungal agent Chaetomium metabolite chemokine receptor 5 antagonist

antifungal agent Chaetomium metabolite chemokine receptor 5 antagonist Show first 5 Terms
inverse is_conjugate_base_of: sch 210971(2-)

sch 210971(2-) Show first 5 Terms
is_conjugate_acid_of: sch 210971(2-)

sch 210971(2-) Show first 5 Terms

Phenotype

Phenotype resulting from sch 210971

Phenotype where environments contain sch 210971

Phenotype modified by environments containing sch 210971

Human Disease / Model Data