Search Ontology:
ChEBI
regorafenib
- Term ID
- CHEBI:68647
- Synonyms
-
- 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide
- BAY 73-4506
- regorafenib
- regorafenibum
- Definition
- A pyridinecarboxamide obtained by condensation of 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]pyridine-2-carboxylic acid with methylamine. Used for for the treatment of metastatic colorectal cancer in patients who have previously received chemotherapy, anti-EGFR or anti-VEGF therapy.
- References
-
- CAS:755037-03-7
- Drug_Central:4654
- KEGG:D10138
- LINCS:LSM-1226
- PMID:21170960
- PMID:21419931
- PMID:21752724
- PMID:22421192
- PMID:22568966
- PMID:22577890
- PMID:22612461
- PMID:22614970
- PMID:22706543
- PMID:22777740
- PMID:22785409
- PMID:22959186
- Patent:US2006058358
- Patent:WO2006125540
- Patent:WO2007054216
- Patent:WO2007068380
- Patent:WO2007068382
- Patent:WO2008043446
- Patent:WO2008055629
- Patent:WO2008058644
- Patent:WO2008089388
- Patent:WO2008089389
- Patent:WO2011128261
- Patent:WO2011130728
- Reaxys:14359949
- Wikipedia:Regorafenib
- Ontology
- ChEBI ( EBI )
- is a type of
- has_role
-
- inverse has_part
-
Phenotype
Phenotype resulting from regorafenib
Phenotype where environments contain regorafenib
Phenotype modified by environments containing regorafenib
Human Disease / Model Data