abiraterone

Term ID

CHEBI:68642

Synonyms

(3beta)-17-(pyridin-3-yl)androsta-5,16-dien-3-ol
17-(3-Pyridyl)androsta-5,16-dien-3beta-ol
17-(pyridin-3-yl)androsta-5,16-dien-3beta-ol
abiraterone

Definition

A 3β-sterol that is androsta-5,16-dien-3β-ol substituted at position 17 by a 3-pyridyl group. Administered as the O-acetate, it is used for treatment of metastatic castrate-resistant prostate cancer.

References

cas:154229-19-3
patent:EP1336602
patent:US2011034428
patent:US5604213
patent:WO2012083112
pdb-ccd:AER
pubmed:21093995
pubmed:21239011
pubmed:21242338
pubmed:21326154
pubmed:21612468
pubmed:21729712
pubmed:21743442
pubmed:21807635
pubmed:21808270
pubmed:21857690
pubmed:21864180
pubmed:21864181
pubmed:21864182
pubmed:21878199
pubmed:22002259
pubmed:22170708
pubmed:22266943
pubmed:22331349
pubmed:22373884
pubmed:22402426
pubmed:22411952
pubmed:22451619
pubmed:22500680
pubmed:22611169
pubmed:22753664
pubmed:22763809
pubmed:22822591
pubmed:22915660
pubmed:23024987
reaxys:7309269
wikipedia.en:Abiraterone

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from abiraterone

Phenotype where environments contain abiraterone

Phenotype modified by environments containing abiraterone

Phenotype affecting abiraterone

Human Disease Model