Search Ontology:
ChEBI

boceprevir

Term ID
CHEBI:68621
Synonyms
  • (1R,2S,5S)-N-(4-amino-1-cyclobutyl-3,4-dioxobutan-2-yl)-3-[N-(tert-butylcarbamoyl)-3-methyl-L-valyl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide
  • boceprevir
  • SCH 503034
  • Victrelis
Definition
A synthetic tripeptide consisting of N-(tert-butylcarbamoyl)-3-methyl-L-valyl, a cyclopropyl-fused prolyl and 3-amino-4-cyclobutyl-2-oxobutanamide residues joined in sequence. Used for treatment of chronic hepatitis C virus genotype 1 infection.
References
  • cas:394730-60-0
  • drugcentral:4172
  • kegg.drug:D08876
  • patent:US2005249702
  • patent:US2006275366
  • patent:US2006276404
  • patent:US2006276406
  • patent:US2006276407
  • patent:US2006281688
  • patent:US2006281689
  • patent:US2007010431
  • patent:US2007021351
  • patent:US2007149459
  • patent:US2007287664
  • patent:WO2006130553
  • patent:WO2006130688
  • patent:WO2007092616
  • patent:WO2008073282
  • patent:WO2008076316
  • patent:WO2008079216
  • patent:WO2010117936
  • pdb-ccd:HU5
  • pubmed:18201776
  • pubmed:19456105
  • pubmed:20004570
  • pubmed:20945949
  • pubmed:21123164
  • pubmed:21828346
  • pubmed:22095516
  • pubmed:22169996
  • pubmed:22222799
  • pubmed:22239501
  • pubmed:22349607
  • pubmed:22383557
  • pubmed:22392426
  • pubmed:22397560
  • pubmed:22404758
  • pubmed:22506260
  • pubmed:22515132
  • pubmed:22537438
  • pubmed:22570678
  • pubmed:22576324
  • pubmed:22770811
  • pubmed:22799589
  • pubmed:22975763
  • pubmed:23001704
  • pubmed:23016967
  • reaxys:10502086
  • wikipedia.en:Boceprevir
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from boceprevir
Phenotype where environments contain boceprevir
Phenotype modified by environments containing boceprevir
Phenotype affecting boceprevir
Human Disease Model