linagliptin

Term ID

CHEBI:68610

Synonyms

(R)-8-(3-aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methylquinazolin-2-ylmethyl)-3,7-dihydro-purine-2,6-dione
8-[(3R)-3-aminopiperidin-1-yl]-7-(but-2-yn-1-yl)-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-3,7-dihydro-1H-purine-2,6-dione
BI 1356
linagliptin
Tradjenta

Definition

A xanthine that is 7H-xanthine bearing (4-methylquinazolin-2-yl)methyl, methyl, but-2-yn-1-yl and 3-aminopiperidin-1-yl substituents at positions 1, 3, 7 and 8 respectively (the R-enantiomer). Used for treatment of type II diabetes.

References

cas:668270-12-0
kegg.drug:D09566
patent:EP1852108
patent:EP246874
patent:US2007259900
patent:US2012165525
patent:WO2004018468
patent:WO2006048427
patent:WO2009022008
patent:WO2010072776
pdb-ccd:356
pubmed:19476474
pubmed:19552619
pubmed:19732457
pubmed:19771584
pubmed:19777398
pubmed:19947894
pubmed:20086031
pubmed:20160157
pubmed:20497745
pubmed:20538719
pubmed:20637971
pubmed:20875371
pubmed:21053992
pubmed:21059094
pubmed:21084763
pubmed:21114605
pubmed:21205122
pubmed:21306414
pubmed:21340661
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pubmed:21410628
pubmed:21443284
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pubmed:21603986
pubmed:21642558
pubmed:21672124
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pubmed:21681003
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pubmed:22022857
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pubmed:22145698
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pubmed:22356132
pubmed:22420306
pubmed:22440191
pubmed:22482239
pubmed:22493041
pubmed:22498683
pubmed:22541836
pubmed:22568694
pubmed:22587735
pubmed:22651241
pubmed:22691164
pubmed:22748821
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pubmed:22761701
pubmed:22804249
pubmed:22816729
pubmed:22879795
pubmed:22913735
pubmed:22926098
pubmed:22939034
pubmed:22974280
pubmed:22986920
pubmed:22997980
pubmed:23033241
reaxys:11300181
wikipedia.en:Linagliptin

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from linagliptin

Phenotype where environments contain linagliptin

Phenotype modified by environments containing linagliptin

Phenotype affecting linagliptin

Human Disease Model