telaprevir

Term ID

CHEBI:68595

Synonyms

• (1S,3aR,6aS)-(2S)-2-cyclohexyl-N-(pyrazinylcarbonyl)glycyl-3-methyl-L-valyl-N-((1S)-1-((cyclopropylamino)oxoacetyl)butyl)octahydrocyclopenta(c)pyrrole-1-carboxamide
• (1S,3aR,6aS)-2-[(2S)-2-({(2S)-2-cyclohexyl-2-[(pyrazin-2-ylcarbonyl)amino]acetyl}amino)-3,3-dimethylbutanoyl]-N-[(3S)-1-(cyclopropylamino)-1,2-dioxohexan-3-yl]octahydrocyclopenta[c]pyrrole-1-carboxamide
• Incivek
• VX 950
• VX-950

Definition

An oligopeptide consisting of N-(pyrazin-2-ylcarbonyl)cyclohexylalanyl, 3-methylvalyl, octahydrocyclopenta[c]pyrrole-1-carboxy, and 3-amino-N-cyclopropyl-2-oxohexanamide residues joined in sequence. Used for treatment of chronic hepatitis C virus genotype 1 infection.

References

• CAS:402957-28-2
• Drug_Central:4173
• HMDB:HMDB0015616
• KEGG:D09012
• PMID:20945948
• PMID:21884670
• PMID:21940388
• PMID:22039291
• PMID:22095516
• PMID:22169996
• PMID:22180548
• PMID:22212567
• PMID:22222799
• PMID:22239508
• PMID:22345334
• PMID:22383557
• PMID:22404758
• PMID:22423262
• PMID:22439668
• PMID:22471376
• PMID:22506260
• PMID:22511937
• PMID:22515133
• PMID:22537438
• PMID:22642697
• PMID:22806681
• PMID:22889114
• PMID:22902721
• PMID:22954756
• PMID:23016967
• PMID:25017682
• Patent:US2005197301
• Patent:US2006252698
• Patent:US2006276405
• Patent:US2006276407
• Patent:US2006281688
• Patent:US2007087973
• Patent:WO2005025517
• Patent:WO2006127289
• Patent:WO2011103932
• Reaxys:10511882
• Wikipedia:Telaprevir

Ontology

ChEBI  ( EBI )