rivaroxaban

Term ID

CHEBI:68579

Synonyms

• 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide
• BAY 59-7939
• BAY59-7939
• rivaroxaban
• Xarelto

Definition

A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-chlorothiophene-2-carboxylic acid with the amino group of 4-{4-[(5S)-5-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl}morpholin-3-one. An anticoagulant used for prophylaxis of venous thromboembolism in patients with knee or hip replacement surgery.

References

• cas:366789-02-8
• drugbank:DB06228
• drugcentral:4182
• kegg.drug:D07086
• lincs.smallmolecule:LSM-5499
• patent:EP1685841
• patent:US2005182055
• patent:US2007026065
• patent:US2009036504
• patent:US2010151011
• patent:US2011034453
• patent:US2011112083
• patent:US2011152266
• patent:US2011288294
• patent:US7816355
• patent:WO2004060887
• patent:WO2005068456
• patent:WO2008140220
• patent:WO2011080341
• patent:WO2012035057
• patent:WO2012051692
• pdb-ccd:RIV
• pmc:PMC7292653
• pubmed:22042412
• pubmed:22173426
• pubmed:22187012
• pubmed:22242932
• pubmed:22272729
• pubmed:22372178
• pubmed:22387577
• pubmed:22422332
• pubmed:22533680
• pubmed:22534269
• pubmed:22534775
• pubmed:22542983
• pubmed:22651881
• pubmed:22664783
• pubmed:22701330
• pubmed:22740145
• pubmed:22777255
• pubmed:22800431
• pubmed:22811404
• pubmed:22871192
• pubmed:22884545
• pubmed:22932305
• pubmed:22958812
• pubmed:23006523
• pubmed:23014816
• pubmed:30653475
• pubmed:31784708
• pubmed:32002769
• pubmed:32023227
• pubmed:32223113
• pubmed:32223511
• pubmed:32252075
• pubmed:32265542
• pubmed:32279215
• pubmed:32296145
• pubmed:32382756
• pubmed:32519800
• pubmed:32548552
• pubmed:32548556
• reaxys:10206739
• wikipedia.en:Rivaroxaban

Ontology

ChEBI  ( EBI )