ticagrelor

Term ID

CHEBI:68558

Synonyms

• (1S,2S,3R,5S)-3-(7-((1R,2S)-2-(3,4-Difluorophenyl)cyclopropylamino)-5-(propylthio)-3H-(1,2,3)triazolo(4,5-d)pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
• (1S,2S,3R,5S)-3-[7-{[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino}-5-(propylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
• AZD 6140
• AZD-6140
• AZD6140
• Brilinta
• ticagrelor

Definition

A triazolopyrimidine that is an adenosine isostere; the cyclopentane ring is similar to ribose and the nitrogen-rich [1,2,3]triazolo[4,5-d]pyrimidine moiety resembles the nucleobase adenine. A platelet aggregation inhibitor which is used for prevention of thromboembolic events in patients with acute coronary syndrome.

References

• cas:274693-27-5
• drugcentral:4184
• hmdb:HMDB0015702
• kegg.drug:D09017
• patent:WO2012085665
• pubmed:22991347
• reaxys:15468079

Ontology

ChEBI  ( EBI )