teriflunomide

Term ID

CHEBI:68540

Synonyms

(2Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide
(Z)-2-cyano-alpha,alpha,alpha-trifluoro-3-hydroxy-p-crotonotoluidide
A 77-1726
A 771726
Aubagio
HMR 1726
HMR1726
teriflunomida
teriflunomide
teriflunomidum

(all 10)

Definition

An enamide obtained by formal condensation of the carboxy group of (2Z)-2-cyano-3-hydroxybut-2-enoic acid with the anilino group of 4-(trifluoromethyl)aniline. Used for the treatment of relapsing forms of multiple sclerosis and rheumatoid arthritis.

References

(all 30)

Ontology

ChEBI ( EBI )

Relationships

is a type of: (trifluoromethyl)benzenes aromatic amide enamide enol nitrile ... Show All 6 Terms

(trifluoromethyl)benzenes aromatic amide enamide enol nitrile secondary carboxamide Show first 5 Terms
has_role: drug metabolite EC 1.3.98.1 [dihydroorotate oxidase (fumarate)] inhibitor hepatotoxic agent non-steroidal anti-inflammatory drug tyrosine kinase inhibitor

drug metabolite EC 1.3.98.1 [dihydroorotate oxidase (fumarate)] inhibitor hepatotoxic agent non-steroidal anti-inflammatory drug tyrosine kinase inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from teriflunomide

Phenotype where environments contain teriflunomide

Phenotype modified by environments containing teriflunomide

Phenotype affecting teriflunomide

Human Disease Model