Search Ontology:
ChEBI

teriflunomide

Term ID
CHEBI:68540
Synonyms
  • (2Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide
  • (Z)-2-cyano-alpha,alpha,alpha-trifluoro-3-hydroxy-p-crotonotoluidide
  • A 77-1726
  • A 771726
  • Aubagio
  • HMR 1726
  • HMR1726
  • teriflunomida
  • teriflunomide
  • teriflunomidum
Definition
An enamide obtained by formal condensation of the carboxy group of (2Z)-2-cyano-3-hydroxybut-2-enoic acid with the anilino group of 4-(trifluoromethyl)aniline. Used for the treatment of relapsing forms of multiple sclerosis and rheumatoid arthritis.
References
  • cas:163451-81-8
  • drugcentral:4634
  • kegg.drug:D10172
  • pdb-ccd:A26
  • pubmed:20880295
  • pubmed:21349677
  • pubmed:21367665
  • pubmed:21425264
  • pubmed:21625416
  • pubmed:21991951
  • pubmed:22012334
  • pubmed:22052286
  • pubmed:22052362
  • pubmed:22148963
  • pubmed:22229697
  • pubmed:22278631
  • pubmed:22307384
  • pubmed:22398660
  • pubmed:22426573
  • pubmed:22612746
  • pubmed:22622860
  • pubmed:22673950
  • pubmed:22723573
  • pubmed:22766059
  • pubmed:22784880
  • pubmed:22796174
  • pubmed:22960763
  • pubmed:22965070
  • reaxys:6655982
  • wikipedia.en:Teriflunomide
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from teriflunomide
Phenotype where environments contain teriflunomide
Phenotype modified by environments containing teriflunomide
Phenotype affecting teriflunomide
Human Disease Model