platencin

Term ID

CHEBI:68241

Synonyms

• (-)-platencin
• 2,4-dihydroxy-3-({3-[(4aS,8S,8aR)-8-methyl-3-methylidene-7-oxo-1,3,4,7,8,8a-hexahydro-2H-2,4a-ethanonaphthalen-8-yl]propanoyl}amino)benzoic acid

Definition

A monocarboxylic acid amide obtained by the formal condensation of the amino group of 3-amino-2,4-dihydroxybenzoic acid with the carboxy group of the polycyclic cage component. It is an antibiotic isolated from Streptomyces platensis and exhibits inhibitory activity against fatty acid synthase.

References

• cas:869898-86-2
• chemspider:20576369
• knapsack:C00056080
• patent:CA2770486
• pdb-ccd:N32
• pubmed:17456595
• pubmed:19581087
• pubmed:21214253
• pubmed:21322068
• pubmed:21915133
• pubmed:22999174
• pubmed:23382856
• pubmed:23834636
• pubmed:25361063
• pubmed:25393231
• pubmed:26404223
• pubmed:28237556
• pubmed:28465627
• pubmed:30216060
• pubmed:30735041
• pubmed:30816397
• pubmed:31061542
• pubmed:31237717
• pubmed:31291107
• pubmed:33523676
• reaxys:11140608

Ontology

ChEBI  ( EBI )