(+)-lyoniresinol

Term ID

CHEBI:68168

Synonyms

(6R,7R,8S)-8-(4-hydroxy-3,5-dimethoxyphenyl)-6,7-bis(hydroxymethyl)-1,3-dimethoxy-5,6,7,8-tetrahydronaphthalen-2-ol

Definition

A lignan that is tetralin substituted by a 4-hydroxy-3,5-dimethoxy group at position 4, hydroxymethyl groups at positions 2 and 3, methoxy groups at positions 5 and 7 and a hydroxy group at position 6. Isolated from Machilus robusta and Sinocalamus affinis, it exhibits antineoplastic activity.

References

PMID:21469695
PMID:21627109
Patent:JP2010150152
Reaxys:2191984

Ontology

ChEBI ( EBI )

Relationships

is a type of: dimethoxybenzene lignan polyphenol primary alcohol tetralins

dimethoxybenzene lignan polyphenol primary alcohol tetralins Show first 5 Terms
has_role: antineoplastic agent metabolite

antineoplastic agent metabolite Show first 5 Terms
inverse has_functional_parent: (+)-lyoniresinol 4,4'-bis-O-beta-D-glucopyranoside (+)-lyoniresinol-3-alpha-O-beta-D-glucopyranoside

(+)-lyoniresinol 4,4'-bis-O-beta-D-glucopyranoside (+)-lyoniresinol-3-alpha-O-beta-D-glucopyranoside Show first 5 Terms

Phenotype

Phenotype resulting from (+)-lyoniresinol

Phenotype where environments contain (+)-lyoniresinol

Phenotype modified by environments containing (+)-lyoniresinol

Human Disease Model