5E-7-oxozeaenol

Term ID

CHEBI:67558

Synonyms

(2E,5S,6S,8E,11S)-5,6,15-trihydroxy-17-methoxy-11-methyl-12-oxabicyclo[12.4.0]octadeca-1(18),2,8,14,16-pentaene-7,13-dione
(3S,5E,8S,9S,11E)-8,9,16-trihydroxy-14-methoxy-3-methyl-3,4,9,10-tetrahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione
LL-Z1640-1

Definition

A macrolide that is the 7-oxo derivative of zeaenol (the 5E stereoisomer). Isolated from Fungi, it exhibits cytotoxic, antibacterial and inhibitory activity against NF-kappaB.

References

PMID:21513293
Reaxys:5452473

Ontology

ChEBI ( EBI )

Relationships

is a type of: aromatic ether macrolide phenols secondary alcohol secondary alpha-hydroxy ketone

aromatic ether macrolide phenols secondary alcohol secondary alpha-hydroxy ketone Show first 5 Terms
has_role: antibacterial agent antineoplastic agent metabolite NF-kappaB inhibitor

antibacterial agent antineoplastic agent metabolite NF-kappaB inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from 5E-7-oxozeaenol

Phenotype where environments contain 5E-7-oxozeaenol

Phenotype modified by environments containing 5E-7-oxozeaenol

Human Disease Model