Search Ontology:
ChEBI
dolastatin 10
- Term ID
- CHEBI:67357
- Synonyms
-
- DLS-10
- dolastatin-10
- N,N-dimethyl-L-valyl-N-[(3R,4S,5S)-3-methoxy-1-{(2S)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-{[(1S)-2-phenyl-1-(1,3-thiazol-2-yl)ethyl]amino}propyl]pyrrolidin-1-yl}-5-methyl-1-oxoheptan-4-yl]-N-methyl-L-valinamide
- Definition
- A tetrapeptide that is isolated from the sea hare Dolabella auricularia. It is a potent anticancer agent which inhibits tubulin polymerization.
- References
-
- cas:110417-88-4
- chemspider:7986684
- drugbank:DB12730
- kegg.compound:C11280
- knapsack:C00044726
- lincs.smallmolecule:LSM-45943
- pubmed:21472238
- pubmed:21534541
- pubmed:2353935
- pubmed:25431858
- pubmed:28682414
- pubmed:28885014
- pubmed:29454703
- pubmed:30023909
- pubmed:31460552
- pubmed:31830440
- pubmed:32026730
- pubmed:32323990
- pubmed:8471072
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from dolastatin 10
Phenotype where environments contain dolastatin 10
Phenotype modified by environments containing dolastatin 10
Phenotype affecting dolastatin 10
Human Disease Model